Assay Report Card

Basic Information

ID: ALA4013582

Type: Binding

Description: Non-competitive inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in HEK293F cells using peptide substrate preincubated for 15 mins followed by substrate/[3H]-SAM addition measured after 60 mins under varying concentration of peptide

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
371.423.093.09