Basic Information
ID: ALA4013728
Type: Binding
Description: Inhibition of IL15R/IL15 interaction in human NK92 cells assessed as reduction of IL15-induced STAT5 phosphorylation preincubated for 30 mins with IL15 followed by cell addition measured after 1 hr by AlphaScreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4013728
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 615.63 | 7.20 | 7.20 |
| 562.78 | 5.17 | 5.17 |
| 564.71 | 4.74 | 4.74 |
| 604.87 | 6.34 | 6.34 |
| 562.74 | 5.51 | 5.51 |
| 576.77 | 5.76 | 5.76 |
| 540.64 | 5.00 | 5.00 |
| 662.45 | 6.25 | 6.25 |
| 545.67 | 5.67 | 5.67 |
| 534.69 | 4.73 | 4.73 |
| 478.62 | 2.83 | 2.83 |
| 550.69 | 4.44 | 4.44 |
| 562.74 | 5.51 | 5.51 |
| 576.72 | 4.90 | 4.90 |
| 553.13 | 5.69 | 5.69 |
| 489.39 | 3.69 | 3.69 |
| 573.55 | 6.03 | 6.03 |