Basic Information
ID: ALA4013784
Type: ADME
Description: Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay relative to serotonin
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Serotonin 2b (5-HT2b) receptor(ALA1833)
Document: ALA4011649
Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay relative to serotonin: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013784
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.69 | 2.59 | 2.59 |
| 377.89 | 4.29 | 4.29 |
| 346.83 | 3.60 | 3.60 |
| 372.87 | 4.28 | 4.28 |
| 377.91 | 4.94 | 4.94 |
| 365.88 | 3.78 | 3.78 |
| 245.72 | 2.16 | 2.16 |
| 383.87 | 4.08 | 4.08 |
| 271.76 | 2.69 | 2.69 |
| 383.87 | 4.08 | 4.08 |
| 364.85 | 2.83 | 2.83 |
| 316.38 | 3.13 | 3.13 |
| 351.85 | 3.74 | 3.74 |