Prodrug activation in human serum assessed as 3-chlorobenzyl (S)-3-cyclohexyl-1-oxo-1-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-ylamino)propan-2...

Basic Information

ID: ALA4013963

Type: ADME

Description: Prodrug activation in human serum assessed as 3-chlorobenzyl (S)-3-cyclohexyl-1-oxo-1-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-ylamino)propan-2-ylcarbamate formation by measuring parent compound half life at 25 to 100 uM by LC-MS method

Format: BAO_0000366

Organism: Homo sapiens

Tissue: Serum

Target:  Serum(ALA613426)

Document:  ALA4011653

Prodrug activation in human serum assessed as 3-chlorobenzyl (S)-3-cyclohexyl-1-oxo-1-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-ylamino)propan-2-ylcarbamate formation by measuring parent compound half life at 25 to 100 uM by LC-MS method: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
638.113.083.08
624.092.692.69