Basic Information
ID: ALA4013964
Type: ADME
Description: Prodrug activation human liver microsomes assessed as 3-chlorobenzyl (S)-3-cyclohexyl-1-oxo-1-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-ylamino)propan-2-ylcarbamate formation at 25 to 100 uM after 1 hr in the presence of NADPH by LC-MS method
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsome
Target: Liver(ALA613419)
Document: ALA4011653
Prodrug activation human liver microsomes assessed as 3-chlorobenzyl (S)-3-cyclohexyl-1-oxo-1-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-ylamino)propan-2-ylcarbamate formation at 25 to 100 uM after 1 hr in the presence of NADPH by LC-MS method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4013964
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 680.20 | 4.25 | 4.25 |