Basic Information
ID: ALA4014035
Type: Binding
Description: Inhibition of PDE5A1 catalytic domain (535 to 860 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]cGMP as substrate after 15 mins by liquid scintillation counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4014035
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 666.71 | 1.61 | 1.61 |
| 374.42 | 4.69 | 4.69 |
| 445.52 | 3.74 | 3.74 |
| 384.39 | 4.34 | 4.34 |
| 368.39 | 4.63 | 4.63 |
| 402.84 | 5.29 | 5.29 |
| 349.34 | 3.36 | 3.36 |
| 430.53 | 6.17 | 6.17 |
| 398.42 | 4.64 | 4.64 |
| 402.84 | 5.29 | 5.29 |
| 426.42 | 6.01 | 6.01 |
| 369.38 | 4.03 | 4.03 |
| 368.39 | 4.63 | 4.63 |
| 385.39 | 5.38 | 5.38 |
| 443.50 | 3.49 | 3.49 |
| 373.37 | 3.93 | 3.93 |
| 402.84 | 5.29 | 5.29 |
| 404.42 | 3.04 | 3.04 |
| 368.39 | 4.63 | 4.63 |
| 402.43 | 4.72 | 4.72 |
| 381.43 | 5.55 | 5.55 |
| 402.84 | 5.29 | 5.29 |