Basic Information
ID: ALA4014240
Type: Binding
Description: Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain shedding of membrane bound AP-TGFalpha after 1 hr relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4014240
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 523.60 | 4.47 | 4.47 |
| 545.61 | 5.01 | 5.01 |
| 629.60 | 4.63 | 4.63 |
| 607.98 | 5.12 | 5.12 |
| 588.55 | 4.05 | 4.05 |
| 567.57 | 4.12 | 4.12 |
| 591.53 | 4.61 | 4.61 |
| 705.74 | 7.43 | 7.43 |
| 603.56 | 4.48 | 4.48 |
| 663.66 | 6.44 | 6.44 |
| 629.64 | 5.77 | 5.77 |
| 587.56 | 4.78 | 4.78 |
| 607.98 | 5.12 | 5.12 |
| 749.79 | 8.10 | 8.10 |
| 573.54 | 4.47 | 4.47 |
| 607.98 | 5.12 | 5.12 |
| 601.59 | 5.03 | 5.03 |
| 539.52 | 3.34 | 3.34 |
| 587.56 | 4.78 | 4.78 |
| 629.64 | 5.77 | 5.77 |
| 652.43 | 5.23 | 5.23 |
| 649.63 | 6.14 | 6.14 |
| 571.56 | 4.27 | 4.27 |
| 598.55 | 4.34 | 4.34 |
| 705.74 | 7.43 | 7.43 |
| 587.56 | 4.78 | 4.78 |
| 642.43 | 5.78 | 5.78 |
| 725.73 | 7.80 | 7.80 |
| 699.43 | 5.07 | 5.07 |
| 579.58 | 4.39 | 4.39 |