Basic Information
ID: ALA4014480
Type: Binding
Description: Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after 7 days by SRB assay
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4014272
Inhibition of ABCB1 in human MCF7/ADR cells assessed as potentiation of vinblastine-induced cytotoxicity by measuring vinblastine IC50 at IC10 after 7 days by SRB assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4014480
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.50 | 2.84 | 2.84 |
| 362.52 | 5.04 | 5.04 |
| 299.80 | 4.40 | 4.40 |
| 363.51 | 3.41 | 3.41 |
| 350.51 | 4.89 | 4.89 |
| 336.48 | 4.50 | 4.50 |
| 407.56 | 3.16 | 3.16 |
| 393.53 | 2.77 | 2.77 |
| 223.28 | 3.30 | 3.30 |
| 348.49 | 4.65 | 4.65 |
| 364.49 | 3.88 | 3.88 |
| 368.48 | 2.45 | 2.45 |
| 350.46 | 3.49 | 3.49 |
| 377.53 | 3.80 | 3.80 |
| 313.83 | 4.79 | 4.79 |