Basic Information
ID: ALA4014684
Type: Binding
Description: Inhibition of recombinant HIV-1 group M subtype B RT-RNase H activity expressed in Escherichia coli M15 using 18-nucleotide 3'-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5'-dabsyl-labeled DNA as substrate measured after 1 hr
Organism: HIV-1 group M
Activity Charts
Bioactivity
Activity Types for Assay ALA4014684
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 152.15 | 1.21 | 1.21 |
| 194.19 | 1.50 | 1.50 |
| 222.24 | 1.98 | 1.98 |
| 456.71 | 7.23 | 7.23 |
| 456.71 | 7.09 | 7.09 |
| 298.34 | 3.20 | 3.20 |
| 315.68 | 4.07 | 4.07 |
| 178.19 | 1.61 | 1.61 |
| 412.70 | 7.80 | 7.80 |
| 472.71 | 6.20 | 6.20 |
| 290.49 | 6.12 | 6.12 |
| 390.56 | 6.66 | 6.66 |
| 446.67 | 8.22 | 8.22 |
| 268.48 | 6.02 | 6.02 |
| 418.62 | 7.44 | 7.44 |
| 312.37 | 3.51 | 3.51 |
| 332.78 | 3.85 | 3.85 |
| 334.46 | 5.10 | 5.10 |
| 466.66 | 8.10 | 8.10 |
| 452.64 | 7.80 | 7.80 |
| 359.81 | 3.29 | 3.29 |
| 348.40 | 4.35 | 4.35 |
| 596.76 | 9.46 | 9.46 |
| 312.37 | 3.51 | 3.51 |
| 362.51 | 5.88 | 5.88 |
| 430.63 | 7.69 | 7.69 |
| 429.65 | 7.26 | 7.26 |
| 574.76 | 9.35 | 9.35 |
| 444.66 | 7.99 | 7.99 |
| 443.67 | 7.57 | 7.57 |