Basic Information
ID: ALA4014719
Type: ADME
Description: Inhibition of full length human C-terminal His-tagged KDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) expressed in baculovirus expression system at 30 uM using FITC-p53 acetylated peptide as substrate after 60 mins by microfluidic assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4014719
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 279.34 | 1.81 | 1.81 |
| 357.40 | 2.21 | 2.21 |
| 332.81 | 3.35 | 3.35 |
| 272.16 | 3.52 | 3.52 |
| 261.24 | 2.51 | 2.51 |
| 319.43 | 4.25 | 4.25 |
| 326.35 | 4.01 | 4.01 |
| 286.24 | 2.55 | 2.55 |
| 293.30 | 1.99 | 1.99 |
| 322.34 | 2.71 | 2.71 |
| 339.18 | 3.11 | 3.11 |
| 253.21 | 2.91 | 2.91 |
| 237.28 | 2.48 | 2.48 |
| 287.28 | 1.62 | 1.62 |
| 291.31 | 0.36 | 0.36 |
| 308.29 | 3.71 | 3.71 |
| 265.22 | 1.32 | 1.32 |
| 362.48 | 3.87 | 3.87 |
| 277.27 | 2.77 | 2.77 |
| 269.25 | 1.51 | 1.51 |
| 241.25 | 1.41 | 1.41 |
| 251.34 | 2.45 | 2.45 |
| 241.32 | 3.02 | 3.02 |
| 288.31 | 0.87 | 0.87 |
| 326.35 | 3.12 | 3.12 |
| 274.28 | 0.63 | 0.63 |
| 302.29 | 0.85 | 0.85 |
| 350.33 | 4.29 | 4.29 |
| 303.78 | 2.70 | 2.70 |
| 307.16 | 2.27 | 2.27 |
| 352.35 | 3.16 | 3.16 |
| 310.25 | 3.73 | 3.73 |
| 324.34 | 1.62 | 1.62 |
| 257.10 | 1.24 | 1.24 |
| 387.46 | 1.52 | 1.52 |
| 306.45 | 2.16 | 2.16 |
| 239.23 | 1.58 | 1.58 |
| 361.94 | 3.77 | 3.77 |
| 283.09 | 1.92 | 1.92 |
| 383.21 | 1.13 | 1.13 |
| 315.72 | 3.86 | 3.86 |
| 354.25 | 3.12 | 3.12 |