Assay Report Card

Basic Information

ID: ALA4014727

Type: Binding

Description: Inhibition of Schistosoma mansoni KDAC8 using (FAM)-labeled peptide as substrate after 60 mins by microfluidic assay

Organism: Schistosoma mansoni

Activity Charts

Bioactivity

Activity Types for Assay ALA4014727

IC50

Total(169)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
264.32	2.47	2.47
302.37	2.58	2.58
236.27	2.48	2.48
376.42	3.34	3.34
319.41	1.79	1.79
326.35	2.50	2.50
313.36	1.80	1.80
307.39	1.94	1.94
280.39	2.23	2.23
250.30	2.86	2.86
349.43	3.33	3.33
622.88	5.03	5.03
326.40	4.09	4.09
278.36	3.50	3.50
335.23	3.41	3.41
335.41	2.80	2.80
227.67	2.67	2.67
296.33	2.82	2.82
378.47	2.51	2.51
389.48	4.08	4.08
353.42	3.26	3.26
508.58	-1.60	-1.60
531.70	3.24	3.24
508.58	-1.60	-1.60
242.28	2.42	2.42
234.30	2.55	2.55
248.33	2.86	2.86
256.26	2.06	2.06
270.29	2.37	2.37
286.29	2.07	2.07
274.25	2.20	2.20
290.71	2.71	2.71
335.16	2.82	2.82
324.26	3.08	3.08
300.31	2.46	2.46
314.34	2.85	2.85
314.34	2.85	2.85
321.34	2.91	2.91
362.39	3.73	3.73
316.31	2.08	2.08
320.73	2.72	2.72
320.73	2.72	2.72
355.18	3.37	3.37
362.39	3.73	3.73
330.34	2.47	2.47
300.31	2.00	2.00
320.73	2.72	2.72
396.83	4.29	4.29
382.80	4.50	4.50
382.80	4.50	4.50
325.15	3.36	3.36
335.70	2.62	2.62
359.60	4.02	4.02
376.41	4.12	4.12
188.19	1.35	1.35
273.29	2.39	2.39
336.37	1.92	1.92
238.27	1.24	1.24
347.42	3.83	3.83
322.41	3.66	3.66
394.43	2.97	2.97
453.61	4.45	4.45
310.42	3.60	3.60
470.57	5.10	5.10
422.49	2.18	2.18
407.51	3.96	3.96
408.46	2.03	2.03
464.56	4.62	4.62
294.31	2.32	2.32
673.82	7.19	7.19
452.62	5.11	5.11
649.79	7.08	7.08
131.18	1.07	1.07
378.47	4.15	4.15
392.50	4.24	4.24
436.55	4.40	4.40
480.57	4.64	4.64
450.54	2.18	2.18
465.55	3.65	3.65
587.75	4.77	4.77
364.45	3.60	3.60
687.86	5.42	5.42
406.53	4.63	4.63
308.34	2.71	2.71
350.42	3.51	3.51
407.51	4.54	4.54
323.35	2.13	2.13
424.46	1.81	1.81
484.60	5.19	5.19
465.55	5.83	5.83
478.59	4.70	4.70
365.43	2.93	2.93
422.53	4.31	4.31
395.46	2.30	2.30
393.49	3.57	3.57
392.50	4.54	4.54
338.48	4.38	4.38
309.33	1.74	1.74
308.33	2.17	2.17
513.64	5.33	5.33
565.67	6.47	6.47
440.54	4.83	4.83
470.53	3.77	3.77
521.66	5.28	5.28
350.42	3.21	3.21
437.54	3.73	3.73
672.83	7.86	7.86
479.58	4.04	4.04
431.50	2.88	2.88
425.55	3.67	3.67
408.46	1.79	1.79
522.65	4.61	4.61
292.38	3.89	3.89
409.44	2.39	2.39
649.79	7.38	7.38
394.43	1.64	1.64
370.45	4.45	4.45
364.45	3.97	3.97
292.38	3.89	3.89
364.45	3.97	3.97
392.50	4.54	4.54
195.22	0.69	0.69
350.42	3.58	3.58
549.67	6.73	6.73
507.63	5.19	5.19
423.47	2.78	2.78
407.51	3.96	3.96
351.41	2.55	2.55
410.54	4.25	4.25
512.65	6.00	6.00
309.33	1.74	1.74
426.52	4.74	4.74
424.57	4.34	4.34
650.78	6.41	6.41
635.76	6.99	6.99
464.56	4.31	4.31
485.58	4.52	4.52
238.27	1.24	1.24
457.53	3.86	3.86
323.35	2.13	2.13
580.69	5.90	5.90
558.69	7.12	7.12
442.51	3.95	3.95
397.50	2.84	2.84
498.62	5.91	5.91
381.43	1.91	1.91
664.81	6.80	6.80
579.70	6.56	6.56
350.42	3.58	3.58
398.51	5.26	5.26
450.54	4.23	4.23
535.65	6.34	6.34
336.39	3.13	3.13
408.45	3.36	3.36
663.82	7.47	7.47
324.40	1.08	1.08
441.53	4.16	4.16
422.53	3.04	3.04
701.89	5.50	5.50
406.53	4.63	4.63
308.34	2.71	2.71
438.48	2.20	2.20
438.59	5.03	5.03
623.80	3.07	3.07
294.31	2.32	2.32
702.88	4.84	4.84
508.58	-1.60	-1.60
658.80	7.77	7.77