Basic Information
ID: ALA4014731
Type: ADME
Description: Inhibition of human CYP2D6 expressed in yeast microsomal membranes at 10 uM using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate by fluorescence assay relative to control
Organism: Homo sapiens
Subcellular Fraction: Microsomal Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4014731
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.24 | 2.50 | 2.50 |
| 223.24 | 2.40 | 2.40 |
| 301.14 | 3.35 | 3.35 |
| 238.25 | 2.30 | 2.30 |
| 238.25 | 2.30 | 2.30 |
| 268.27 | 2.30 | 2.30 |
| 413.26 | 5.70 | 5.70 |
| 346.36 | 1.94 | 1.94 |
| 378.41 | 3.36 | 3.36 |
| 358.40 | 4.18 | 4.18 |
| 276.30 | 2.60 | 2.60 |
| 394.38 | 4.46 | 4.46 |
| 268.27 | 2.30 | 2.30 |
| 306.32 | 2.61 | 2.61 |
| 364.35 | 4.45 | 4.45 |
| 427.29 | 5.48 | 5.48 |
| 362.36 | 4.53 | 4.53 |
| 394.38 | 4.46 | 4.46 |
| 383.23 | 5.69 | 5.69 |
| 376.39 | 4.32 | 4.32 |