Basic Information
ID: ALA4015044
Type: Binding
Description: Inhibition of PI3Kalpha mutant in human BT474 cells assessed as decrease in AKT phosphorylation at Thr308 after 2 hrs
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015044
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 525.55 | 3.72 | 3.72 |
| 507.56 | 3.58 | 3.58 |
| 513.54 | 3.31 | 3.31 |
| 465.53 | 3.81 | 3.81 |
| 538.60 | 3.64 | 3.64 |
| 539.58 | 3.85 | 3.85 |
| 447.54 | 3.67 | 3.67 |
| 507.56 | 3.58 | 3.58 |
| 483.52 | 3.95 | 3.95 |
| 481.50 | 3.71 | 3.71 |
| 465.53 | 3.81 | 3.81 |