Basic Information
ID: ALA4015147
Type: Binding
Description: Inhibition of human URAT1 expressed in HEK293T cells assessed as reduction in [14C]uric acid uptake measured after 5 mins by liquid scintillation counting method
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4015147
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.09 | 5.46 | 5.46 |
| 278.33 | 2.13 | 2.13 |
| 278.33 | 2.13 | 2.13 |
| 332.30 | 3.02 | 3.02 |
| 351.43 | 3.93 | 3.93 |
| 337.40 | 3.54 | 3.54 |
| 316.30 | 3.14 | 3.14 |
| 335.39 | 3.42 | 3.42 |
| 301.17 | 2.37 | 2.37 |
| 323.38 | 3.14 | 3.14 |
| 332.30 | 3.02 | 3.02 |
| 410.46 | 4.45 | 4.45 |
| 403.44 | 4.71 | 4.71 |
| 327.29 | 2.88 | 2.88 |
| 316.30 | 3.14 | 3.14 |
| 377.35 | 4.03 | 4.03 |
| 365.46 | 4.17 | 4.17 |
| 353.38 | 3.56 | 3.56 |
| 266.30 | 2.26 | 2.26 |
| 355.13 | 3.26 | 3.26 |
| 273.32 | 1.99 | 1.99 |
| 385.45 | 4.57 | 4.57 |