Basic Information
ID: ALA4015186
Type: Binding
Description: Inhibition of mouse TRPC4beta expressed in HEK293 cells co-expressing MOR assessed as decrease in DAMGO-evoked membrane depolarization at 22 uM preincubated for 2 mins followed by DAMGO addition measured for 2.5 mins by FLIPR membrane potential dye-based fluorescence assay relative to control
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4015186
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.51 | 5.07 | 5.07 |
| 448.45 | 4.77 | 4.77 |