Assay Report Card

Basic Information

ID: ALA4015187

Type: Binding

Description: Inhibition of mouse TRPM8 expressed in HEK293 cells assessed as decrease in methanol-evoked increase in intracellular calcium level at 22 uM preincubated for 2 mins followed by methanol addition measured for 2.5 mins by Fluo8-AM dye-based fluorescence assay relative to control

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
398.443.893.89
460.515.075.07
448.454.774.77