Assay Report Card

Basic Information

ID: ALA4015211

Type: Binding

Description: Antagonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as channel desensitization at 20 to 100 uM at +80 mV in presence of 0.1 mM Ca2+ by whole cell patch-clamp method

Organism: Mus musculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
398.443.893.89
476.965.585.58
460.515.075.07
448.454.774.77