ID: ALA4015229
Type: Functional
Description: Positive allosteric modulation of Gi coupled human GPR84 expressed in CHO cells assessed as potentiation of decanoic acid-induced inhibition of forskolin-induced cAMP accumulation by measuring decanoic acid EC50 at 0.3 uM after 15 mins in presence of [3H]-cAMP by radiometric assay (Rvb = 9.22 to 13.1 uM)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4015229
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
246.31 | 4.24 | 4.24 |
318.27 | 4.80 | 4.80 |