Basic Information
ID: ALA4015427
Type: Binding
Description: Inhibition of recombinant human NLRP3 ATPase assessed as hydrolysis of ATP at 50 uM preincubated for 15 mins followed by addition of ATP measured after 40 mins by ADP-Glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015427
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 207.25 | 1.81 | 1.81 |
| 193.16 | 1.66 | 1.66 |
| 240.69 | 2.49 | 2.49 |
| 275.13 | 3.15 | 3.15 |
| 144.13 | -0.11 | -0.11 |
| 340.80 | 3.47 | 3.47 |
| 375.25 | 4.12 | 4.12 |
| 212.63 | 2.01 | 2.01 |
| 254.71 | 3.15 | 3.15 |
| 282.72 | 3.06 | 3.06 |
| 226.70 | 3.08 | 3.08 |
| 247.08 | 2.67 | 2.67 |
| 252.70 | 2.90 | 2.90 |
| 196.63 | 2.52 | 2.52 |
| 198.65 | 2.60 | 2.60 |
| 224.69 | 3.00 | 3.00 |