Basic Information
ID: ALA4015430
Type: Binding
Description: Inhibition of NLRP3 inflammasome in LPS-primed C57BL/6 mouse bone marrow derived macrophages assessed as reduction in nigericin-induced IL-1beta production at 10 uM preincubated for 1 hr followed by stimulation with nigericin measured after 30 mins by ELISA
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4015430
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.69 | 3.00 | 3.00 |