Basic Information
ID: ALA4015436
Type: Binding
Description: Inhibition of NLRP3 inflammasome in LPS-primed C57BL/6 mouse bone marrow derived macrophages assessed as reduction in nigericin-induced caspase-1 activation at 10 to 100 uM preincubated for 1 hr followed by stimulation with nigericin measured after 30 mins by Western blot analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4015436
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.69 | 3.00 | 3.00 |