Basic Information
ID: ALA4015439
Type: Binding
Description: Inhibition of NLRP3 in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-induced IL-1beta gene expression at 10 to 100 uM preincubated for 30 mins followed by LPS stimulation measured after 4 hrs by qRT-PCR analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4015439
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.69 | 3.00 | 3.00 |