Basic Information
ID: ALA4015447
Type: Binding
Description: Inhibition of recombinant YFP-tagged NLRP3 (unknown origin) expressed in HEK293 cells co-expressing luciferase assessed as reduction in nigericin-induced intracellular K+ decrease-mediated conformational changes in protein at 10 to 100 uM measured after 24 hrs by BRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015447
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.69 | 3.00 | 3.00 |