Basic Information
ID: ALA4015448
Type: Binding
Description: Inhibition of recombinant YFP-tagged NLRP3 (unknown origin) expressed in HEK293 cells co-expressing luciferase assessed as initial conformational changes in protein by measuring increase in nigericin-induced decrease in intracellular K+ level at 10 to 100 uM measured after 24 hrs by BRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015448
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 224.69 | 3.00 | 3.00 |