Basic Information
ID: ALA4015488
Type: Binding
Description: Inhibition of NLRP3 inflammasome in LPS-primed C57BL/6 mouse bone marrow derived macrophages assessed as reduction in nigericin-induced pyroptosis at 10 to 100 uM preincubated for 1 hr followed by stimulation with ATP measured after 30 mins by LDH release assay
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA4015488
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 207.25 | 1.81 | 1.81 |
| 224.69 | 3.00 | 3.00 |