Basic Information
ID: ALA4015644
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount method
Format: BAO_0000219
Organism: Homo sapiens
Target: Sodium/glucose cotransporter 2(ALA3884)
Document: ALA4014312
Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4015644
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.88 | 1.84 | 1.84 |
| 436.89 | 1.36 | 1.36 |
| 444.52 | 2.97 | 2.97 |
| 424.95 | 3.17 | 3.17 |
| 466.91 | 1.33 | 1.33 |
| 478.93 | 1.74 | 1.74 |
| 454.88 | 2.11 | 2.11 |
| 516.02 | 3.51 | 3.51 |
| 472.87 | 2.56 | 2.56 |
| 461.90 | 1.86 | 1.86 |
| 514.91 | 2.33 | 2.33 |
| 452.96 | 2.68 | 2.68 |
| 436.89 | 1.97 | 1.97 |
| 492.95 | 2.13 | 2.13 |
| 402.44 | 1.31 | 1.31 |
| 482.93 | 2.89 | 2.89 |
| 450.92 | 2.36 | 2.36 |
| 468.91 | 2.50 | 2.50 |
| 462.93 | 2.50 | 2.50 |
| 528.93 | 2.72 | 2.72 |