Basic Information
ID: ALA4015669
Type: Binding
Description: Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex after 1 hr by scintillation counting method
Format: BAO_0000357
Organism: Homo sapiens
Target: DNA (cytosine-5)-methyltransferase 1(ALA1993)
Document: ALA4014314
Inhibition of full length His-tagged human DNMT1 using SAM/[methyl-3H]SAM assessed as reduction of methylation in biotinylated hemimethylated DNA duplex after 1 hr by scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4015669
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 567.14 | 6.69 | 6.69 |
| 596.78 | 7.58 | 7.58 |
| 606.77 | 6.44 | 6.44 |
| 532.69 | 6.04 | 6.04 |
| 597.77 | 7.06 | 7.06 |
| 546.72 | 6.43 | 6.43 |
| 562.72 | 6.04 | 6.04 |
| 560.75 | 6.73 | 6.73 |
| 567.14 | 6.69 | 6.69 |
| 594.76 | 7.66 | 7.66 |
| 547.71 | 5.90 | 5.90 |