Basic Information
ID: ALA4015670
Type: Binding
Description: Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site after 1 hr by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015670
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 567.14 | 6.69 | 6.69 |
| 596.78 | 7.58 | 7.58 |
| 606.77 | 6.44 | 6.44 |
| 532.69 | 6.04 | 6.04 |
| 597.77 | 7.06 | 7.06 |
| 546.72 | 6.43 | 6.43 |
| 562.72 | 6.04 | 6.04 |
| 560.75 | 6.73 | 6.73 |
| 567.14 | 6.69 | 6.69 |
| 594.76 | 7.66 | 7.66 |
| 547.71 | 5.90 | 5.90 |