ID: ALA4015671
Type: Binding
Description: Inhibition of human DNMT3A catalytic domain using AdoMet assessed as reduction of methylation in 5'-biotin/3' 6-carboxyfluorescein labeled DNA duplex at CpG site at 32 uM after 1 hr by fluorescence assay relative to control
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4015671
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
461.53 | 5.65 | 5.65 |
576.75 | 6.43 | 6.43 |
611.77 | 4.68 | 4.68 |
518.67 | 5.99 | 5.99 |
546.72 | 6.43 | 6.43 |
545.73 | 7.03 | 7.03 |
588.80 | 7.10 | 7.10 |
577.69 | 5.94 | 5.94 |
510.69 | 5.46 | 5.46 |
546.72 | 6.43 | 6.43 |
564.71 | 6.56 | 6.56 |
567.14 | 6.69 | 6.69 |
596.78 | 7.58 | 7.58 |
567.14 | 6.69 | 6.69 |
546.72 | 6.43 | 6.43 |
581.16 | 7.08 | 7.08 |
470.62 | 5.20 | 5.20 |
518.67 | 5.79 | 5.79 |
606.77 | 6.44 | 6.44 |
614.72 | 7.44 | 7.44 |
510.69 | 5.58 | 5.58 |
547.70 | 5.78 | 5.78 |
574.77 | 7.04 | 7.04 |
574.77 | 7.16 | 7.16 |
601.80 | 6.46 | 6.46 |
532.69 | 6.04 | 6.04 |
546.72 | 6.43 | 6.43 |
557.70 | 4.04 | 4.04 |
562.72 | 6.13 | 6.13 |
548.74 | 6.37 | 6.37 |
547.71 | 5.62 | 5.62 |
597.77 | 7.06 | 7.06 |
578.72 | 5.84 | 5.84 |
630.84 | 5.61 | 5.61 |
561.73 | 5.33 | 5.33 |
496.66 | 5.27 | 5.27 |
546.72 | 6.43 | 6.43 |
562.72 | 6.04 | 6.04 |
560.75 | 6.73 | 6.73 |
545.73 | 7.03 | 7.03 |
567.14 | 6.69 | 6.69 |
614.72 | 7.44 | 7.44 |
594.76 | 7.66 | 7.66 |
547.71 | 5.90 | 5.90 |
428.54 | 3.96 | 3.96 |
503.65 | 6.52 | 6.52 |
517.63 | 3.31 | 3.31 |
546.72 | 6.43 | 6.43 |
506.65 | 5.69 | 5.69 |
560.75 | 6.45 | 6.45 |