Basic Information
ID: ALA4015696
Type: Binding
Description: Inhibition of recombinant human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux at 10 mM preincubated for 30 mins followed by Hoechst 33342 addition measured immediately at 60 sec time interval for 120 mins by fluorescence assay relative to Ko143
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015696
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 469.58 | 3.64 | 3.64 |
| 297.36 | 5.04 | 5.04 |
| 313.36 | 4.75 | 4.75 |
| 356.39 | 4.22 | 4.22 |
| 328.38 | 4.44 | 4.44 |
| 356.39 | 4.22 | 4.22 |
| 342.36 | 4.13 | 4.13 |
| 323.36 | 4.31 | 4.31 |
| 396.37 | 5.46 | 5.46 |
| 261.33 | 4.20 | 4.20 |
| 314.35 | 4.14 | 4.14 |
| 292.34 | 3.60 | 3.60 |
| 366.35 | 5.45 | 5.45 |
| 323.36 | 4.31 | 4.31 |
| 328.38 | 3.93 | 3.93 |
| 286.34 | 4.07 | 4.07 |
| 358.36 | 4.65 | 4.65 |
| 328.38 | 4.44 | 4.44 |
| 343.35 | 4.34 | 4.34 |
| 366.35 | 5.45 | 5.45 |
| 314.35 | 4.14 | 4.14 |
| 342.36 | 4.13 | 4.13 |
| 380.40 | 4.09 | 4.09 |
| 343.35 | 4.34 | 4.34 |
| 292.34 | 3.60 | 3.60 |
| 323.36 | 4.31 | 4.31 |
| 343.35 | 4.34 | 4.34 |
| 358.40 | 4.45 | 4.45 |
| 358.40 | 4.45 | 4.45 |
| 287.33 | 3.46 | 3.46 |
| 359.35 | 4.05 | 4.05 |
| 328.38 | 3.93 | 3.93 |
| 315.35 | 5.18 | 5.18 |
| 322.37 | 4.91 | 4.91 |
| 322.32 | 3.81 | 3.81 |
| 323.36 | 4.31 | 4.31 |
| 328.38 | 4.44 | 4.44 |
| 286.34 | 4.07 | 4.07 |
| 341.42 | 4.50 | 4.50 |
| 316.34 | 4.57 | 4.57 |
| 328.38 | 4.44 | 4.44 |
| 343.35 | 4.34 | 4.34 |
| 398.47 | 5.39 | 5.39 |
| 358.40 | 4.45 | 4.45 |