Basic Information
ID: ALA4015697
Type: Binding
Description: Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels preincubated for 30 mins followed by calcein AM addition measured immediately at 60 sec time interval for 60 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015697
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1202.63 | ||
| 356.39 | 4.22 | 4.22 |
| 342.36 | 4.13 | 4.13 |
| 396.37 | 5.46 | 5.46 |
| 328.38 | 4.44 | 4.44 |
| 358.40 | 4.45 | 4.45 |
| 358.40 | 4.45 | 4.45 |
| 328.38 | 4.44 | 4.44 |
| 328.38 | 4.44 | 4.44 |
| 398.47 | 5.39 | 5.39 |
| 358.40 | 4.45 | 4.45 |