Basic Information
ID: ALA4015698
Type: Binding
Description: Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels at 10 uM preincubated for 30 mins followed by calcein AM addition measured immediately at 60 sec time interval for 60 mins by fluorescence assay relative to Cyclosporine A
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015698
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.39 | 4.22 | 4.22 |
| 342.36 | 4.13 | 4.13 |
| 396.37 | 5.46 | 5.46 |
| 328.38 | 4.44 | 4.44 |
| 358.40 | 4.45 | 4.45 |
| 358.40 | 4.45 | 4.45 |
| 328.38 | 4.44 | 4.44 |
| 328.38 | 4.44 | 4.44 |
| 398.47 | 5.39 | 5.39 |
| 358.40 | 4.45 | 4.45 |