Basic Information
ID: ALA4015725
Type: Binding
Description: Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling preincubated for 30 mins followed by LPS stimulation measured after overnight incubation by secreted embryonic alkaline phosphatase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015725
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1119.21 | 11.80 | 11.80 |
| 1247.43 | ||
| 908.81 | 5.95 | 5.95 |
| 998.89 | 4.83 | 4.83 |
| 1191.32 | ||
| 1035.05 | 9.46 | 9.46 |