Basic Information
ID: ALA4015727
Type: Binding
Description: Binding affinity to CD14/MD2 (unknown origin) expressed in HEK-Blue cells co-expressing TLR4 assessed as inhibition of LPS-induced TLR4 signaling at 0.1 to 100 uM preincubated for 30 mins followed by LPS stimulation measured after overnight incubation by secreted embryonic alkaline phosphatase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015727
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 924.95 | 11.03 | 11.03 |
| 1009.11 | 13.37 | 13.37 |
| 1177.43 |