Basic Information
ID: ALA4015729
Type: Binding
Description: Binding affinity to CD14/MD2 in human PBMC assessed as inhibition of LPS-induced TLR4 signaling by measuring decrease in TNFalpha secretion at 1 to 10 uM preincubated for 30 mins followed by LPS stimulation for 18 hrs by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015729
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 908.81 | 5.95 | 5.95 |
| 1035.05 | 9.46 | 9.46 |