Basic Information
ID: ALA4015733
Type: Binding
Description: Binding affinity to CD14/MD2 in Balb/c mouse splenocytes assessed as inhibition of LPS-induced TLR4-MyD88 pathway by measuring reduction in TNFalpha expression at 1 to 10 uM preincubated for 30 mins followed by LPS stimulation for 5 hrs by qRT-PCR method
Organism: Mus musculus
Strain: Balb/c
Activity Charts
Bioactivity
Activity Types for Assay ALA4015733
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 908.81 | 5.95 | 5.95 |
| 1035.05 | 9.46 | 9.46 |