Basic Information
ID: ALA4015778
Type: Binding
Description: Inhibition of SMRT2 H1426W mutant peptide binding to N-terminal His6-tagged human BCL6 BTB domain C8Q/C67R/C84N mutant expressed in Escherichia coli BL21 (DE3) preincubated for 30 mins followed by SMRT2 H1426W mutant peptide addition measured after 60 mins by time-resolved fluorescence resonance energy transfer assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4015778
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.45 | 2.19 | 2.19 |
| 368.82 | 2.34 | 2.34 |
| 431.46 | 2.67 | 2.67 |
| 588.07 | 3.91 | 3.91 |
| 268.32 | 1.78 | 1.78 |
| 510.98 | 2.94 | 2.94 |
| 304.36 | 2.94 | 2.94 |
| 587.08 | 4.51 | 4.51 |
| 444.54 | 2.94 | 2.94 |
| 515.53 | 2.62 | 2.62 |
| 388.43 | 2.89 | 2.89 |
| 418.46 | 2.25 | 2.25 |
| 472.51 | 2.10 | 2.10 |
| 607.67 | 3.74 | 3.74 |
| 418.46 | 2.25 | 2.25 |
| 403.45 | 2.19 | 2.19 |
| 551.05 | 3.72 | 3.72 |
| 464.53 | 2.49 | 2.49 |
| 601.11 | 4.82 | 4.82 |
| 312.33 | 1.23 | 1.23 |
| 624.14 | 3.03 | 3.03 |
| 418.46 | 2.25 | 2.25 |
| 459.51 | 3.00 | 3.00 |
| 334.38 | 2.31 | 2.31 |
| 326.36 | 1.62 | 1.62 |
| 496.96 | 2.92 | 2.92 |
| 199.22 | 1.18 | 1.18 |
| 617.11 | 4.52 | 4.52 |
| 489.54 | 2.36 | 2.36 |
| 457.49 | 2.77 | 2.77 |
| 487.52 | 2.13 | 2.13 |
| 601.05 | 4.36 | 4.36 |
| 601.11 | 4.82 | 4.82 |
| 498.97 | 3.14 | 3.14 |
| 373.42 | 2.83 | 2.83 |
| 629.06 | 4.84 | 4.84 |