Basic Information
ID: ALA4016144
Type: Binding
Description: Inhibition of 5-LOX-mediated LTB4 production in arachidonic acid-stimulated RBL1 cells at 10 uM preincubated for 2 hrs followed by A23187 induction for 15 mins by LC/MS/MS analysis relative to control
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA4016144
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.28 | 3.07 | 3.07 |
| 395.69 | 4.22 | 4.22 |
| 478.85 | 4.42 | 4.42 |
| 338.72 | 4.62 | 4.62 |
| 344.12 | 4.66 | 4.66 |
| 357.16 | 5.57 | 5.57 |
| 373.62 | 6.09 | 6.09 |
| 361.12 | 5.40 | 5.40 |
| 343.13 | 5.26 | 5.26 |
| 325.14 | 5.12 | 5.12 |
| 339.17 | 5.43 | 5.43 |
| 355.17 | 5.13 | 5.13 |
| 319.19 | 4.85 | 4.85 |
| 322.72 | 4.92 | 4.92 |
| 392.69 | 5.51 | 5.51 |
| 338.72 | 4.62 | 4.62 |
| 304.27 | 3.97 | 3.97 |
| 339.17 | 5.43 | 5.43 |
| 325.14 | 5.12 | 5.12 |
| 307.15 | 4.99 | 4.99 |
| 339.17 | 5.43 | 5.43 |
| 256.25 | 3.82 | 3.82 |
| 325.14 | 5.12 | 5.12 |
| 353.20 | 5.74 | 5.74 |
| 320.73 | 4.48 | 4.48 |
| 389.62 | 5.79 | 5.79 |
| 284.75 | 4.20 | 4.20 |
| 290.70 | 4.47 | 4.47 |
| 254.72 | 4.19 | 4.19 |
| 325.14 | 5.12 | 5.12 |
| 427.13 | 6.16 | 6.16 |
| 359.59 | 5.78 | 5.78 |
| 325.14 | 5.12 | 5.12 |
| 304.73 | 4.78 | 4.78 |
| 343.13 | 5.26 | 5.26 |
| 358.24 | 4.86 | 4.86 |
| 343.13 | 5.26 | 5.26 |
| 343.13 | 5.26 | 5.26 |
| 358.15 | 4.97 | 4.97 |
| 409.14 | 6.02 | 6.02 |
| 375.15 | 5.71 | 5.71 |
| 374.70 | 5.37 | 5.37 |
| 359.59 | 5.78 | 5.78 |
| 323.61 | 5.50 | 5.50 |
| 369.20 | 5.44 | 5.44 |
| 392.69 | 5.51 | 5.51 |
| 322.72 | 4.92 | 4.92 |
| 389.62 | 5.79 | 5.79 |
| 339.17 | 5.43 | 5.43 |
| 357.16 | 5.57 | 5.57 |
| 343.13 | 5.26 | 5.26 |
| 304.73 | 4.78 | 4.78 |
| 374.70 | 5.37 | 5.37 |
| 355.17 | 5.13 | 5.13 |
| 325.14 | 5.12 | 5.12 |
| 340.25 | 4.72 | 4.72 |
| 290.70 | 4.47 | 4.47 |
| 339.17 | 5.43 | 5.43 |
| 339.17 | 5.43 | 5.43 |
| 373.62 | 6.09 | 6.09 |
| 308.69 | 4.61 | 4.61 |
| 343.13 | 5.26 | 5.26 |
| 318.75 | 5.09 | 5.09 |
| 289.17 | 4.85 | 4.85 |
| 377.58 | 5.92 | 5.92 |
| 307.15 | 4.99 | 4.99 |
| 404.04 | 5.89 | 5.89 |
| 353.20 | 5.69 | 5.69 |
| 339.17 | 5.43 | 5.43 |
| 359.59 | 5.78 | 5.78 |
| 361.12 | 5.40 | 5.40 |
| 373.62 | 6.09 | 6.09 |
| 359.59 | 5.78 | 5.78 |
| 289.17 | 4.85 | 4.85 |