Basic Information
ID: ALA4016279
Type: ADME
Description: Inhibition of human supersomes CYP1A1-mediated 7-ethoxyresorufin conversion to fluorescent resorufin preincubated with 7-ethoxyresorufin for 5 mins followed by addition of NADPH regenerating system measured for 15 mins by EROD assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 1A1(ALA2231)
Document: ALA4014335
Inhibition of human supersomes CYP1A1-mediated 7-ethoxyresorufin conversion to fluorescent resorufin preincubated with 7-ethoxyresorufin for 5 mins followed by addition of NADPH regenerating system measured for 15 mins by EROD assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4016279
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.41 | 2.00 | 2.00 |
| 408.43 | 2.01 | 2.01 |
| 464.54 | 3.52 | 3.52 |
| 450.51 | 3.13 | 3.13 |
| 434.51 | 3.51 | 3.51 |