Basic Information
ID: ALA4017021
Type: Binding
Description: Inhibition of HDAC1/2/3/6 in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4017021
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.53 | 2.18 | 2.18 |
| 417.55 | 3.42 | 3.42 |
| 391.51 | 2.89 | 2.89 |
| 389.50 | 2.64 | 2.64 |
| 363.46 | 2.11 | 2.11 |
| 440.54 | 2.58 | 2.58 |
| 432.57 | 2.71 | 2.71 |
| 440.54 | 3.21 | 3.21 |
| 479.62 | 4.69 | 4.69 |
| 460.62 | 3.49 | 3.49 |
| 406.53 | 2.18 | 2.18 |
| 457.62 | 4.35 | 4.35 |
| 425.53 | 3.13 | 3.13 |
| 439.56 | 3.80 | 3.80 |
| 417.55 | 3.26 | 3.26 |
| 425.53 | 3.76 | 3.76 |
| 465.59 | 4.38 | 4.38 |