Basic Information
ID: ALA4017035
Type: Binding
Description: Inhibition of HDAC1/2/3/6 in human CAL27 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 250 nM preincubated for 48 hrs followed by cisplatin addition measured after 72 hrs by MTT assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4017035
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.54 | 2.58 | 2.58 |