Assay Report Card

Basic Information

ID: ALA4017036

Type: Binding

Description: Inhibition of HDAC1/2/3/6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 250 nM preincubated for 48 hrs followed by cisplatin addition measured after 72 hrs by MTT assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
440.542.582.58