Assay Report Card

Basic Information

ID: ALA4017152

Type: Binding

Description: Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 1 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay relative to cisplatin alone

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
264.322.472.47
362.392.362.36