Assay Report Card

Basic Information

ID: ALA4017153

Type: Binding

Description: Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring fold reduction in cisplatin IC50 at 0.5 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay relative to cisplatin alone

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.442.682.68
376.412.672.67