Assay Report Card

Basic Information

ID: ALA4017221

Type: Binding

Description: Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of 1 uM cisplatin-induced cytotoxicity by measuring combination index at 700 uM preincubated for 48 hrs followed by cisplatin treatment measured after 72 hrs by MTT assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.442.682.68
362.392.362.36
376.412.672.67