Assay Report Card

Basic Information

ID: ALA4017275

Type: Binding

Description: Inhibition of HDAC1/HDAC6 in human Cal27CisR cells assessed as potentiation of cisplatin-induced apoptosis at 0.5 uM preincubated for 48 hrs followed by cisplatin treatment for 6 hrs measured after 24 hrs by propidium iodide dye-based flow cytometry (Rvb = 20.3%)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.442.682.68
376.412.672.67