Inhibition of fatty acid synthase in rat cytosolic hepatic extracts using acetyl CoA and malonyl CoA as substrate preincubated for 30 mins followed by...

Basic Information

ID: ALA4017566

Type: Binding

Description: Inhibition of fatty acid synthase in rat cytosolic hepatic extracts using acetyl CoA and malonyl CoA as substrate preincubated for 30 mins followed by acetyl CoA addition and subsequent incubation for 3 mins prior to malonyl CoA addition measured after 10 mins in presence of NADPH by spectrophotometric method

Format: BAO_0000019

Organism: Rattus norvegicus

Target: Fatty acid synthase(ALA3783)

Document: ALA4017443

Inhibition of fatty acid synthase in rat cytosolic hepatic extracts using acetyl CoA and malonyl CoA as substrate preincubated for 30 mins followed by acetyl CoA addition and subsequent incubation for 3 mins prior to malonyl CoA addition measured after 10 mins in presence of NADPH by spectrophotometric method: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4017566

IC50

Total(6)

Parent Molecular Weight	ALogP	Polar Surface Area
254.33	2.92	2.92
268.40	3.61	3.61
240.34	2.83	2.83
240.34	2.83	2.83
254.37	3.22	3.22
240.34	2.83	2.83

Parent Molecular Weight

ALogP

Polar Surface Area

254.33

2.92

268.40

3.61

240.34

2.83

240.34

2.83

254.37

3.22

240.34

2.83

Inhibition of fatty acid synthase in rat cytosolic hepatic extracts using acetyl CoA and malonyl CoA as substrate preincubated for 30 mins followed by...

Basic Information

Activity Charts

Compound Summary