Assay Report Card

Basic Information

ID: ALA4017851

Type: Binding

Description: Inhibition of RND efflux pump in Pseudomonas aeruginosa PAO1 assessed as potentiation of minocycline-induced antibacterial activity by measuring minocycline MIC at 8 ug/ml after 18 to 24 hrs by microbroth dilution assay (Rvb = 8 ug/ml)

Organism: Pseudomonas aeruginosa PAO1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
329.373.333.33
226.322.242.24
1064.38
1031.22-1.74-1.74
975.11-3.30-3.30
1630.25-0.18-0.18
430.552.832.83
1059.27-0.96-0.96
1115.380.600.60
1003.16-2.52-2.52
1181.961.681.68