Assay Report Card

Basic Information

ID: ALA4017856

Type: Binding

Description: Inhibition of RND efflux pump in Pseudomonas aeruginosa PAO1 assessed as potentiation of tigecycline-induced antibacterial activity by measuring fold reduction in tigecycline MIC at 8 ug/ml after 18 to 24 hrs by microbroth dilution assay relative to tigecycline alone

Organism: Pseudomonas aeruginosa PAO1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1064.38
1115.380.600.60
1181.961.681.68