Assay Report Card

Basic Information

ID: ALA4017904

Type: Binding

Description: Inhibition of RND efflux pump in Klebsiella pneumoniae isolate 116381 assessed as potentiation of minocycline-induced antibacterial activity by measuring minocycline MIC at 8 ug/ml after 18 to 24 hrs by microbroth dilution assay (Rvb = 128 ug/ml)

Organism: Klebsiella pneumoniae

Strain: isolate 116381

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
329.373.333.33
226.322.242.24
1064.38
430.552.832.83
1115.380.600.60
1181.961.681.68